diff --git a/libnetwork/controller.go b/libnetwork/controller.go
index 2e485a7336..156232e982 100644
--- a/libnetwork/controller.go
+++ b/libnetwork/controller.go
@@ -100,6 +100,23 @@ type Controller struct {
 	diagnosticServer *diagnostic.Server
 	mu               sync.Mutex
 
+	// endpoints is an in-memory cache of Endpoint. Do not use this map unless
+	// you're sure your code is thread-safe.
+	//
+	// The data persistence layer is instantiating new Endpoint objects every
+	// time it loads an object from its store or in-memory cache. This leads to
+	// multiple instances representing the same endpoint to concurrently live
+	// in memory. As such, the Endpoint mutex might be ineffective and not
+	// correctly protect against data races.
+	//
+	// If you want to use this map for new or existing code, you need to make
+	// sure: 1. the Endpoint object is correctly locked; 2. the lock order
+	// between Sandbox, Network and Endpoint is the same as the rest of the
+	// code (in order to avoid deadlocks).
+	endpoints map[string]*Endpoint
+	// endpointsMu protects the endpoints map.
+	endpointsMu sync.Mutex
+
 	// FIXME(thaJeztah): defOsSbox is always nil on non-Linux: move these fields to Linux-only files.
 	defOsSboxOnce sync.Once
 	defOsSbox     *osl.Namespace
@@ -118,6 +135,7 @@ func New(cfgOptions ...config.Option) (*Controller, error) {
 		cfg:              cfg,
 		store:            store,
 		sandboxes:        map[string]*Sandbox{},
+		endpoints:        map[string]*Endpoint{},
 		svcRecords:       make(map[string]*svcInfo),
 		serviceBindings:  make(map[serviceKey]*service),
 		agentInitDone:    make(chan struct{}),
diff --git a/libnetwork/endpoint.go b/libnetwork/endpoint.go
index 3ac2c2112a..c100fd0235 100644
--- a/libnetwork/endpoint.go
+++ b/libnetwork/endpoint.go
@@ -582,7 +582,7 @@ func (ep *Endpoint) sbJoin(ctx context.Context, sb *Sandbox, options ...Endpoint
 		return errdefs.System(err)
 	}
 
-	if err := n.getController().updateToStore(ctx, ep); err != nil {
+	if err := n.getController().storeEndpoint(ctx, ep); err != nil {
 		return err
 	}
 
@@ -762,7 +762,7 @@ func (ep *Endpoint) rename(name string) error {
 	ep.mu.Unlock()
 
 	// Update the store with the updated name
-	if err := ep.getNetwork().getController().updateToStore(context.TODO(), ep); err != nil {
+	if err := ep.getNetwork().getController().storeEndpoint(context.TODO(), ep); err != nil {
 		return err
 	}
 
@@ -798,7 +798,7 @@ func (ep *Endpoint) UpdateDNSNames(dnsNames []string) error {
 	}
 
 	// Update the store with the updated name
-	if err := c.updateToStore(context.TODO(), ep); err != nil {
+	if err := c.storeEndpoint(context.TODO(), ep); err != nil {
 		return err
 	}
 
@@ -904,7 +904,7 @@ func (ep *Endpoint) sbLeave(ctx context.Context, sb *Sandbox, force bool) error
 	// spurious logs when cleaning up the sandbox when the daemon
 	// ungracefully exits and restarts before completing sandbox
 	// detach but after store has been updated.
-	if err := n.getController().updateToStore(ctx, ep); err != nil {
+	if err := n.getController().storeEndpoint(ctx, ep); err != nil {
 		return err
 	}
 
@@ -1024,14 +1024,14 @@ func (ep *Endpoint) Delete(ctx context.Context, force bool) error {
 		}
 	}
 
-	if err = n.getController().deleteFromStore(ep); err != nil {
+	if err = n.getController().deleteStoredEndpoint(ep); err != nil {
 		return err
 	}
 
 	defer func() {
 		if err != nil && !force {
 			ep.dbExists = false
-			if e := n.getController().updateToStore(context.WithoutCancel(ctx), ep); e != nil {
+			if e := n.getController().storeEndpoint(context.WithoutCancel(ctx), ep); e != nil {
 				log.G(ctx).Warnf("failed to recreate endpoint in store %s : %v", name, e)
 			}
 		}
diff --git a/libnetwork/endpoint_store.go b/libnetwork/endpoint_store.go
new file mode 100644
index 0000000000..3f2fd133f2
--- /dev/null
+++ b/libnetwork/endpoint_store.go
@@ -0,0 +1,41 @@
+package libnetwork
+
+import "context"
+
+// storeEndpoint inserts or updates the endpoint in the store and the in-memory
+// cache maintained by the Controller.
+//
+// This method is thread-safe.
+func (c *Controller) storeEndpoint(ctx context.Context, ep *Endpoint) error {
+	if err := c.updateToStore(ctx, ep); err != nil {
+		return err
+	}
+	c.cacheEndpoint(ep)
+	return nil
+}
+
+// deleteStoredEndpoint deletes the endpoint from the store and the in-memory
+// cache maintained by the Controller.
+//
+// This method is thread-safe.
+func (c *Controller) deleteStoredEndpoint(ep *Endpoint) error {
+	if err := c.deleteFromStore(ep); err != nil {
+		return err
+	}
+
+	c.endpointsMu.Lock()
+	defer c.endpointsMu.Unlock()
+	delete(c.endpoints, ep.id)
+
+	return nil
+}
+
+// cacheEndpoint caches the endpoint in the in-memory cache of endpoints
+// maintained by the Controller.
+//
+// This method is thread-safe.
+func (c *Controller) cacheEndpoint(ep *Endpoint) {
+	c.endpointsMu.Lock()
+	defer c.endpointsMu.Unlock()
+	c.endpoints[ep.id] = ep
+}
diff --git a/libnetwork/endpoint_store_test.go b/libnetwork/endpoint_store_test.go
new file mode 100644
index 0000000000..7372832d6d
--- /dev/null
+++ b/libnetwork/endpoint_store_test.go
@@ -0,0 +1,35 @@
+package libnetwork
+
+import (
+	"context"
+	"testing"
+
+	"github.com/docker/docker/libnetwork/config"
+	"gotest.tools/v3/assert"
+)
+
+func TestEndpointStore(t *testing.T) {
+	configOption := config.OptionDataDir(t.TempDir())
+	c, err := New(configOption)
+	assert.NilError(t, err)
+	defer c.Stop()
+
+	// Insert a first endpoint
+	nw := &Network{id: "testNetwork"}
+	ep1 := &Endpoint{network: nw, id: "testEndpoint1"}
+	err = c.storeEndpoint(context.Background(), ep1)
+	assert.NilError(t, err)
+
+	// Then a second endpoint
+	ep2 := &Endpoint{network: nw, id: "testEndpoint2"}
+	err = c.storeEndpoint(context.Background(), ep2)
+	assert.NilError(t, err)
+
+	// Delete the first endpoint
+	err = c.deleteStoredEndpoint(ep1)
+	assert.NilError(t, err)
+
+	// Store the second endpoint again
+	err = c.storeEndpoint(context.Background(), ep2)
+	assert.NilError(t, err)
+}
diff --git a/libnetwork/network.go b/libnetwork/network.go
index c29c5ea9cc..5577f7fca9 100644
--- a/libnetwork/network.go
+++ b/libnetwork/network.go
@@ -1271,14 +1271,14 @@ func (n *Network) createEndpoint(ctx context.Context, name string, options ...En
 		}
 	}()
 
-	// We should perform updateToStore call right after addEndpoint
+	// We should perform storeEndpoint call right after addEndpoint
 	// in order to have iface properly configured
-	if err = n.getController().updateToStore(ctx, ep); err != nil {
+	if err = n.getController().storeEndpoint(ctx, ep); err != nil {
 		return nil, err
 	}
 	defer func() {
 		if err != nil {
-			if e := n.getController().deleteFromStore(ep); e != nil {
+			if e := n.getController().deleteStoredEndpoint(ep); e != nil {
 				log.G(ctx).Warnf("error rolling back endpoint %s from store: %v", name, e)
 			}
 		}
diff --git a/libnetwork/sandbox_store.go b/libnetwork/sandbox_store.go
index 3239591d2b..7736e477fe 100644
--- a/libnetwork/sandbox_store.go
+++ b/libnetwork/sandbox_store.go
@@ -231,6 +231,7 @@ func (c *Controller) sandboxRestore(activeSandboxes map[string]interface{}) erro
 					},
 					sandboxID: sbs.ID,
 				}
+				c.cacheEndpoint(ep)
 			} else {
 				ep, err = n.getEndpointFromStore(eps.Eid)
 				if err != nil {
@@ -240,6 +241,7 @@ func (c *Controller) sandboxRestore(activeSandboxes map[string]interface{}) erro
 						network:   n,
 						sandboxID: sbs.ID,
 					}
+					c.cacheEndpoint(ep)
 				}
 			}
 			if _, ok := activeSandboxes[sb.ID()]; ok && err != nil {
diff --git a/libnetwork/store.go b/libnetwork/store.go
index 7d0e03e778..30cd8a0943 100644
--- a/libnetwork/store.go
+++ b/libnetwork/store.go
@@ -92,6 +92,7 @@ func (n *Network) getEndpointFromStore(eid string) (*Endpoint, error) {
 	if err != nil {
 		return nil, fmt.Errorf("could not find endpoint %s: %w", eid, err)
 	}
+	n.ctrlr.cacheEndpoint(ep)
 	return ep, nil
 }
 
@@ -110,6 +111,7 @@ func (n *Network) getEndpointsFromStore() ([]*Endpoint, error) {
 	for _, kvo := range kvol {
 		ep := kvo.(*Endpoint)
 		epl = append(epl, ep)
+		n.ctrlr.cacheEndpoint(ep)
 	}
 
 	return epl, nil